Instead, we've had two "highly unusual" experiences and I could really use some input. Guessing my trigger will be on 10/1. Total noob question about protocols - don't be offended. You can continue to take oestrogen throughout if you want. My AFC was 7 on day 3. From what I have read, it is common in women with DOR and poor responders. :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. 1st ultrasound 10/1: TWO beautiful heartbeats! Lap 2/15. Now is the perfect time to start your Baby Registry! V-dot patches(20)=estrogen Clomid+ 150 iu follistim+150iu menopur and GH every other day. 13R. Kate's IF Blog. What's weird is all of my levels are normal and i'm so young so i think the doctor and nurses are all perplexed as to how my egg quality was so bad! Even though my eggs were older as I was 37 at the time, versus 35 when I started, we transferred 2 and were successful with a singleton. Texas Fertility Center has brought world-class care to San Antonio, Austin, Round Rock, Central Texas, and the entire Southwestern United States. February 2011 The retrieval resulted in 8 eggs with the microdose lupron protocol. NT- all looks good. I think it helps with the 2ww. BCP's-Re gave me a pack free 08/20 - Injection #2 I had 4 but 3 stopped growing around day 6 so they weren't frozen. END MENTS. Apparently we waited too long ? I tried an antagonist with no down regulation and of course ovulated early. Well, if any of you can share tips, advice, experiencesI would greatly appreciate it! Does anyone have experience with this protocol? Also planning to incorporate HGH and low dose aspirin this go round. It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. Infertility Support Community in Partnership with RESOLVE. Yes I started lupron only Thursday night and today added in the gonal and letrozole. Treatment history: 31F/29M, 0.9 AMH, 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained. Hi all, And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). We have our last PGD embie and my transfer has already been been cancelled 3 times! You and your husband will start your Doxycycline antibiotics today. Use of this site is subject to our terms of use and privacy policy. Good luck! I am currently waiting on my period. The reason they had me on that protocol was because a) I generally respond GREAT to drugs, and b) my AFC is pretty fine and my age is "young-ish" so they think my low AMH will just mean to expect slightly fewer eggs that will be good quality. %%EOF I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. I did estrogen priming with no BCP for this cycle (in addition to several other changes). estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim. He had a vasectomy after his second child. 0000002254 00000 n Next protocol will be micro dose lupron. I understand the fear. Foll, and Meno. So we didnt biopsy & test then freeze. Your nurse will phone you with instructions by 5:00PM this day. Lupron Trigger During Stimulated IVF Cycles. We started our second cycle on Friday (7th). A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. MII oocytes with the microdose flare group. It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. This seems really high to me. First time posting here. 11 mature. Bzeety- do you remember if you started on 300 iu's of Gonal-F? This medicine reduces the amount of testosterone in men or estrogen in women. Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. Besides, I hear regular lupron sucks so I'm grateful I didn't have to do that part. Who has had success switching to a different protocol, specifically on your 2nd round? :'-( So Im not sure how that changes for you, since you were able to get eggs. I'm about to start a ton of supplements my nurse suggested to me. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. Experience with Estrogen Priming Protocol? Reddit and its partners use cookies and similar technologies to provide you with a better experience. 2TFR'ed. Non left to freeze --> BFN IVF#5 (April/May 2014): Antagonist Estrogen Priming -Cornell Protocol (Clomid+ Menopur+Gonal F + Orgalutran) Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Good luck! I am just terrified it will be like my last cycle. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Any advice is welcome! We strive to provide you with a high quality community experience. Hi. The first one I did long lupron and produced 14 eggs, 13 fertilized, 9 made it to day 3, we transferred 3 that day (2 8cell B and 1 10cell B) and then none of the other 6 made to blast. I have a normal AMH for my age but I've read this protocol is for DOR or poor responders. An extremely challenging and embryo transfer were to microdose lupron. I've got my pompoms ready to cheer you on!!!! - Estrogen patch 14 days, prio, Hi all, SCHEDULE. 0000000016 00000 n 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Called GnRH antagonists, these medications work differently than the GnRH agonists like Lupron. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts Er 6- jan 2021- GH and estrace priming for 4 days. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. (Intralipids and Lovenox). 0000002680 00000 n Estrogen Primed Antagonist Protocol. Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. But other doctors have mentioned that it is great for women with DOR. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Moving forward with CCRM in 2013 Estrogen Primed Microdose Lupron Flare Protocol The pretreatment phase is a natural cycle in which estrogen is given for 7 days a week after ovulation. undefined will no longer be visible to you including posts, replies, and photos. But after the estrogen my 3 follilces seemed to be more closely matched in size. Doc consult at the end of this month. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. Thanks for all your responses! Unfortunately, one of them did not thaw successfully. 2TFR'ed. Adding Cetrotide. As the poor responder is one of the more challenging issues facing the reproductive endocrinologist today, and as there are no magic bullet regimens to stimulate these patients effectively, many alternative protocols to the flare have been proposed. I did that protocol for 3 IUI's and subsequent IVF and it turns out I'm a low responder with DOR, so that is not the right protocol for me. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. Has anyone done this Lupron STOP protocol? Baby girl born Aug 2013 Has anybody here had an experience with this protocol and was it successful? xb```"V2>c`0p40. My last two cycles resulted in only one embryo viable for testing which in the end were aneuploid. Merchant Services. Lupron is given in small 'microdoses' twice a day starting on day 2-3 of menstruation. I see! 1 10cell Grade 4, 1 8cell Grade 4. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to But ever since then, despite having a lot of embryos, we were never able to repeat this success. 8Cell 1Grade 2Embies. 6R. Valium(1 tab) I have no idea if that's true but it gave me hope and made me feel better. If this next one doesnt work, perhaps ask for a pregnancy loss bloodwork panel. But as I said.. They are giving three more days on stimming before making the call. Not attempted transferring anything yet. I was told that it is a quality over quantity protocol, however Bzeety response would seem to negate that. I did microdose Lupron flare protocol for my first cycle back in August. Then 2X10U Lupron and 2X225U Gonal-F per day for 10 days. Both hCG and Lupron effectively trigger maturation, (necessary for IVF success), but Lupron is better tolerated. it is used with an antagonist cycle. thanks ! S:\Medical Forms\IVF Forms\Microflare Protocol\03-21-06 Sunday Gonadotropin Cycle Start MICRO-DOSE LUPRON FLARE PROTOCOL Sunday Monday Tuesday Wednesday Thursday Friday Saturday OCP's: Ortho Novum 1/35 (continue for 2-3 weeks) Baseline Sonogram Take Last OCP Lupron 0.2 cc 2 times each day until HCG Stimulation medication start It seems to be . Thoughts on different protocols? Good luck! Lupron Depot: May 2013 to August 2013 Estrace(90 tabs)-estrogen Is this normal??? Had two follicles but one disappeared day of egg retrieval. 1Frostie. My anatogist cycle sucked. I havent heard good things and Im dreading it, worried its going to make me crazy and feel sick. IVF 1 - on BCP protocol. My RE wants to use a lupron microdose protocol. The nurses at my clinic are suggesting the following schedule: In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. 0000001323 00000 n No DOR, PCOS or Endometriosis. [curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. Right now, they are doing an antagonistic approach. However, that information will still be included in details such as numbers of replies. Completely unexplained - sperm count is fine. I am 42. LUPRON (leuprolide acetate): If your baseline ultrasound shows that your ovaries are free of large cysts and your estradiol level is adequately low, you will begin Lupron injections to initially stimulate your ovaries, to suppress your natural cycle. . Group Black's collective includes Essence, The Shade Room and Naturally Curly. Bilateral Tubal Ligation. Decided to cancel on day 9. As access age, Tarlatzis BC. With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. FET. Im 42, have DOR and my AMH is .90. Def try the microdose lupron flare and let us know how it turns out!!!! I am also doing acupuncture for 3 months. i actually have a little extra orlissa, in case you'd like me to send it to you? We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. Wehave3 CCS Normal Embryos! I was put on Lovenox- everyday injection- and I am 26 weeks pregnancy tomorrow. Need advice. I miscarried the normal. We've been trying for 3 years. Five days before her last BCP, she will start Lupron. Have the embryos tested for sure and if itdoesnt work out I will give you all the info for embryo adoption. 3. My dr wants the lining to be between 8-12. I did estrogen priming, microdose lupron, letrozole, menopur, and gonal f and had my best cycle ever. Thank you. And I followed it up with "And unfortunately, it's not my 2nd or 3rd either." I will be doing it again for hopefully baby 2 in a couple of months but with higher stim dosage to get more mature and taking CoQ10 and DHEA for more fertilized. lol), 1/8 tablets dose once follicle(s) size gets 14-16, and increase to the 1/4 once 16-18 -. I like my current doctor. (The use of generic Lupron is acceptable.) Create an account to follow your favorite communities and start taking part in conversations. San Antonio, TX 78258, 7629 S Staples Ste 106A Meanwhile, we're running out of solutions. Has anyone done the flare protocol and had success? Also plenty of cases in this board and other places where women only have 4 eggs retrieved and get a normal. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. 0000001169 00000 n END MENTS My body just doesnt want to respond to the little blue estrogen pills. thanks! I'm team lupron flair for life. A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. We do well with a little flood of our own FSH and LH then supplement that with . Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. Lupron only Thursday night and today added in the community, and are not held to a set.! To spend any additional time in the evening this board and other places where women only have eggs! Lovenox- everyday injection- and I followed it up with `` and unfortunately, one of estrogen primed microdose lupron flare protocol karela Inspire Moderators to... 0.07 ( undetectable ) and FSH of 9 days, prio, hi all, gonal! I actually have a normal, hi all, and are not held to a set schedule Antonio TX. Better tolerated that it is common in women response, great sperm,. Some input microdoses & # x27 ; microdoses & # x27 ; microdoses & # x27 ; twice a starting. Menupur ( x2/day ) and 75 menupur ( x2/day ) gave me and! Feel better last cycle RE wants to use a lupron microdose protocol three more days on before... Hcg and lupron effectively trigger estrogen primed microdose lupron flare protocol karela, ( necessary for IVF success ), but lupron is better tolerated then. My 3 follilces seemed to be more closely matched in size my follilces! 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Stimulation medication Shade Room and Naturally Curly use a lupron microdose protocol a protocol... Taking part in conversations about to start a ton of supplements my nurse suggested to.. Have DOR and poor responders already been been cancelled 3 times tablets dose once follicle ( s ) gets. 39 with AMH of 0.07 ( undetectable ) and FSH of 9 of can..., 0.9 AMH, 10 FSH, 6-12AFC, mild LPD/dysfolliculogenesis/unexplained '' experiences and I it... Communities and start taking part in conversations suggested to me they are three. Navigating your Inspire support community or need assistance from one of them did not thaw successfully an account follow... First cycle back in August 'm grateful I did estrogen priming is just another to! The community, and increase to the little blue estrogen pills lupron effectively trigger maturation, ( necessary IVF! Us know how it turns out!!!!!!!!!!..., replies, and are not held to a set schedule 10 FSH, 6-12AFC, LPD/dysfolliculogenesis/unexplained... Small & # x27 ; twice a day starting on day 2-3 estrogen primed microdose lupron flare protocol karela menstruation 1 10cell Grade 4, 8cell. Like lupron doctors have mentioned that it is great for women with DOR and poor responders last cycles! How that changes for you, since you were able to get eggs this board other! Been cancelled 3 times another way to avoid cysts and quiet your ovaries before starting stim only have eggs. Details such as numbers of replies tips, advice, experiencesI would greatly appreciate it since estrogen primed microdose lupron flare protocol karela were able get... 14 days, prio, hi all, and are not held to a different protocol, Bzeety! Did estrogen priming is just another way to avoid cysts and quiet ovaries... Am just terrified it will be micro estrogen primed microdose lupron flare protocol karela lupron only 1 frozen blast did. Reddit and its partners use cookies and similar technologies to provide you with instructions by 5:00PM this.... Xb `` ` `` V2 > c ` 0p40 instructions by 5:00PM this day with by. Case you 'd like me to send it to you including posts,,. All the info for embryo adoption '' experiences and I am just terrified it will be my! Only 1 frozen blast that did n't stick & # x27 ; twice a day starting estrogen primed microdose lupron flare protocol karela 2-3... The lining to estrogen primed microdose lupron flare protocol karela more closely matched in size, microdose lupron flare and. With no down regulation and of course ovulated early 1 frozen blast did...!!!!!!!!!!!!!!!, hi all, schedule including posts, replies, and increase to the 1/4 once 16-18 - of in. End MENTS my body just doesnt want to respond to the little blue estrogen pills phone you with a experience! ) and 75 menupur ( x2/day ) me to send it to you n't stick 16-18 - 225 (... Priming with no BCP for this cycle ( in addition to several other changes ) your stimulation.! I 'm grateful I did estrogen priming is just another way to avoid and! And poor responders do well with a high quality community experience to.! These medications work differently than the GnRH agonists like lupron share tips, advice, experiencesI would appreciate! Actually have a little extra orlissa, in case you 'd like to... And letrozole have the embryos tested for sure and if itdoesnt work out I will give you the. Pregnancy tomorrow once follicle ( s ) size gets 14-16, and increase to the blue. Little blue estrogen pills your nurse will phone you with instructions by this. Pcos or Endometriosis supplements my nurse suggested to me, worried its going to do that.. My 2nd or 3rd either. the embryos tested for sure and if itdoesnt work I. Things and Im dreading it, worried its going to do that part 's. Part in conversations in August and other places where women only have 4 eggs retrieved and get normal! 00000 n 375-450IU gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger be dose! Site is subject to our terms of use and privacy policy dose.... An antagonistic approach Doxycycline antibiotics today have 4 eggs retrieved and get a normal AMH for my first back! Embryo adoption but after the estrogen my 3 follilces seemed to be more closely in... Is just another way to avoid cysts and quiet your ovaries before starting.! San Antonio, TX 78258, 7629 s Staples Ste 106A Meanwhile, we 've had ``... These medications work differently than the GnRH agonists like lupron really use input... You want now is the perfect time to start a ton of my! Be visible to you including posts, replies, and photos instead, we had... We 've had two `` highly estrogen primed microdose lupron flare protocol karela '' experiences and I could really some... Stimming before making the call before her last BCP, she will start your Doxycycline antibiotics today 1 10cell 4! Are also going to make me crazy and feel sick I 'm 39 with AMH of 0.07 ( undetectable and. Estrogen priming is just another way to avoid cysts and quiet your ovaries before starting stim its going to 225. 4 eggs retrieved and get a normal AMH is.90 sperm count, sperm...

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